Hrvoje Lusic, Ph.D.

Assistant Professor of Chemistry
Headshot of WPU faculty member, Hrvoje Lusic

Hrvoje “Harry” Lusic was born in Ljubljana, Slovenia. He attended college in the United States, as an undergraduate, on a swimming scholarship. Hrvoje then enrolled at a Ph.D. program at North Carolina State University and completed his studies in 2009. He subsequently worked as a research fellow at Boston University and Harvard Medical School. His research interests are in the field of medicinal and bio-organic chemistry. Hrvoje joined the faculty at WPU in 2018.

Education

  • Ph.D. Chemistry, North Carolina State University
  • MS Polymer Chemistry, Wright State University
  • BS Chemistry, Wright State University

Research & Publications

Publications

  • Rietz, A.; Li, H.; Quist, K.; Cherry, J.; Lorson, C.; Burnett, B.; Kern, N.; Calder, A.; Fritsche, M.; Lusic, H.; Boaler, P.; Choi, S.; Xing, X.; Glicksman, M.; Cuny, G.; Androphy, E.; Hodgetts, K. “Discovery of a Small Molecule Probe that Post-translationally Stabilizes the Survival Motor Neuron Protein for the Treatment of Spinal Muscular Atrophy,” J. Med. Chem. (2017), 60, 4594-4610.
  • Stewart, R. C.; Patwa, A. N.; Lusic, H.; Freedman, J. D.; Wathier, M.; Snyder, B. D.; Guermazi, A.; Grinstaff, M. W. “Synthesis and Pre-clinical Characterization of a Cationic Iodinated Imaging Contrast Agent (CA4+) and Its Use for Quantitative Computed Tomography of Ex Vivo Human Hip Cartilage,” J. Med. Chem. (2017), 60, 5543-5555.
  • Hersey, J. S.; LaManna, C. M.; Lusic, H.; Grinstaff, M. W. “Stimuli responsive charge-switchable lipids: Capture and release of nucleic acids,” Chem. Phys. Lipids (2016), 196, 52-60.
  • Lusic, H.; Freedman, J.; Grinstaff, M. W. “dGEMRIC+: A New Cationic Contrast Agent for Delayed Gadolinium Enhanced Magnetic Resonance Imaging of Cartilage,” Chem. Commun. 2015, 51, 11166-11169.
  • Freedman, J.; Lusic, H.; Snyder, B. D.; Grinstaff, M. W. “Tantalum Oxide Nanoparticles for the Imaging of Articular Cartilage Using X-ray Computed Tomography: Visualization of ex vivo/in vivo Murine Tibia and ex vivo Human Index Finger Cartilage,” Angew. Chem. Int. Edit. 2014, 53, 8406-8410.
  • Govan, J. M; Uprety, R.; Thomas, M.; Lusic, H.; Lively, M. O; Deiters, A. “Cellular Delivery and Photochemical Activation of Antisense Agents Through a Nucleobase Caging Strategy,” ACS Chem. Biol. 2013, 8, 2272-2282.
  • Govan, J. M; Young, D. D; Lusic, H.; Liu, Q.; Lively, M. O; Deiters, A. “Optochemical Control of RNA Interference in Mammalian Cells,” Nucl. Acids Res. 2013, 41, 10518-10528.
  • Lusic, H.; Grinstaff, M. W. “X-Ray Computed Tomography Contrast Agents,” Chem. Rev. 2013, 113, 1641-1666.
  • Stewart, R. C.; Bansal, P. N.; Lusic, H.; Entezari, V.; Snyder, B. D.; Grinstaff, M. W. “Contrast-enhanced CT with a High-Affinity Cationic Contrast Agent for Imaging ex Vivo Bovine, Intact ex Vivo Rabbit, and in Vivo Rabbit Cartilage,” Radiology 2013, 266, 141-150.